I searched for so long and finally found a Solution for modern Systems - Win8.1 x64:
What you need:
dgVoodoo 2 ->
http://dege.freeweb.hu/ - then everything runs smooth.
Blood2ResPatch ->
http://dege.fw.hu/temp/Blood2ResPatch.zip - It fixes the crash on resolutions higher than 1000 rows.
Wobaks Widescreen Solution ->
http://www.mediafire.com/download/qberd ... tch_v2.rar - No stretching.
For the safe Side i have all Files in my Attachments - just copy it into your Blood 2 folder and overwrite everything.