Arcania - Gothic 4 is the successor to Gothic 3 (Gothic 2, Gothic 1) and an Third Person RPG much like Oblivion/Morrowind or Divinity 2. Due to the Gothic 3 bug-desaster, the publisher decided to bring in a new developer.
There is a demo available over at GamersHell: http://www.gamershell.com/download_63874.shtml
The demo is Vert-, which makes it pretty unplayable at 48x10 or similar resolutions. But, there is already a thread in the German support forum about this topic and a official Publisher guy answered:
"Wir haben in der Tat keine native Unterstützung von Eyefinity. Wir werden uns das Thema anschauen und evaluieren, ob ein Fix Sinn macht."
English Translation:
"We indeed do not have native support for Eyefinity. We will look into this topic and evaluate whether a fix makes sense."
The Thread can be found here: http://forum.jowood.com/showthread.php?t=171838
There's also a second thread in the official English forums about the same topic: http://forum.jowood.com/showthread.php?t=171879
Would be nice if some more people would post there... I'm sure they will fix it, if they are seeing demand for it :D